Zachariah Justin P, de Ferranti Sarah D
Department of Cardiology, Boston Children's Hospital, Boston, MA 02445, USA.
Future Cardiol. 2013 Jan;9(1):13-22. doi: 10.2217/fca.12.72.
The report of the National Heart, Lung and Blood Institute Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents collects into one document atherosclerotic disease prevention in pediatric age groups. The guidelines summarize the evidence base and make recommendations that encourage universal adoption of healthier lifestyles, identification of children with cardiovascular disease risk factors, and treatment of those risk factors using targeted lifestyle modification and rarely pharmacotherapy. These recommendations highlight childhood as a frontier for cardiovascular disease prevention. The guideline recommendations are controversial and not universally embraced, but at the very least, they suggest directions for important research. This article explores key facets of the guidelines, controversies and future directions in preventive cardiology for children.
美国国立心肺血液研究所儿童和青少年心血管健康与风险降低综合指南专家小组的报告将儿童年龄组的动脉粥样硬化疾病预防内容汇总在一份文件中。这些指南总结了证据基础,并提出建议,鼓励普遍采用更健康的生活方式,识别有心血管疾病风险因素的儿童,以及通过有针对性的生活方式改变(很少使用药物治疗)来治疗这些风险因素。这些建议突出了儿童期作为心血管疾病预防前沿的地位。指南建议存在争议,并未得到普遍认可,但至少它们为重要研究指明了方向。本文探讨了该指南的关键方面、儿童预防心脏病学中的争议及未来方向。