Memmen J E, McLean I W
Department of Ophthalmology, United States Naval Hospital, Bethesda.
Ophthalmology. 1990 Apr;97(4):429-32. doi: 10.1016/s0161-6420(90)32562-9.
The authors evaluated the long-term results of iridocyclectomy to remove a lesion of the iris or ciliary body in 52 patients. The mean follow-up time was 8.5 years. The excised lesions were benign in 53% of the cases, spindle cell-type melanomas in 19% of the cases, mixed cell- or epithelioid cell-type melanomas in 25%, and an adenocarcinoma of ciliary epithelium in 2%. Visual outcome was generally good, with 43% of the patients achieving visual acuity of 6/7.5 or better and 57% achieving 6/15 or better. In 29% of the patients, enucleation was finally required, and in 10% of the patients there was metastasis of the melanoma. In 11 of the 15 patients who had a subsequent enucleation, the tumor was a melanoma of mixed cell or epithelioid cell type, and in 12 of these 15 patients the surgical margin was involved by the tumor in the iridocyclectomy specimen. All five patients with metastatic disease had melanomas of mixed cell or epithelioid cell type with involvement of the surgical margin in the iridocyclectomy specimen.
作者评估了52例因虹膜或睫状体病变而接受虹膜睫状体切除术的患者的长期结果。平均随访时间为8.5年。切除的病变中，53%为良性，19%为梭形细胞型黑色素瘤，25%为混合细胞型或上皮样细胞型黑色素瘤，2%为睫状体上皮腺癌。视力结果总体良好，43%的患者视力达到6/7.5或更好，57%的患者视力达到6/15或更好。29%的患者最终需要摘除眼球，10%的患者黑色素瘤发生转移。在随后接受眼球摘除术的15例患者中，11例的肿瘤为混合细胞型或上皮样细胞型黑色素瘤，在这15例患者中的12例，虹膜睫状体切除标本的手术切缘被肿瘤累及。所有5例发生转移的患者均为混合细胞型或上皮样细胞型黑色素瘤，虹膜睫状体切除标本的手术切缘被肿瘤累及。
