Institut Curie, UMR 144 CNRS/IC, 26 rue d’Ulm, 75248 Paris Cedex 05, France.
Nat Cell Biol. 2013 Jan;15(1):11-3. doi: 10.1038/ncb2664.
Spindle orientation plays a pivotal role in tissue morphogenesis. An asymmetric anthrax receptor cap is revealed to promote activation of a formin to orient the spindle along the planar cell polarity (PCP) axis in zebrafish dorsal epiblast cells.
纺锤体取向在组织形态发生中起着关键作用。研究揭示，一种不对称炭疽受体帽可促进形成蛋白的激活，从而在斑马鱼背侧外胚层细胞中沿平面细胞极性（PCP）轴定向纺锤体。
