Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, IL 60607-7061, USA.
J Am Chem Soc. 2013 Jan 16;135(2):620-3. doi: 10.1021/ja3113565. Epub 2013 Jan 3.
Iron(II) bromide catalyzes the transformation of ortho-substituted aryl azides into 2,3-disubstituted indoles through a tandem ethereal C-H bond amination [1,2]-shift reaction. The preference for the 1,2-shift component of the tandem reaction was established to be Me < 1° < 2° < Ph.
二价铁溴化物通过串联醚 C-H 键胺化 [1,2]-迁移反应催化邻取代芳基叠氮化物转化为 2,3-二取代吲哚。串联反应中 1,2-迁移组分的优先性为 Me < 1° < 2° < Ph。