Shayegan Amir, Jurysta Cédric, Atash Ramin, Petein Michel, Abbeele Astrid Vanden
Queen Fabiola Children's University Hospital, Department of Pediatric Dentistry, Free University of Brussels, Brussels, Belgium.
Pediatr Dent. 2012 Nov-Dec;34(7):e202-8.
The purpose of this study was to assess and compare, in primary pig teeth, the pulp response after a pulpotomy using either Biodentine (a new tricalcium-silicate cement), white mineral trioxide aggregate (WMTA), or formocresol (FC) and repeat the same after direct pulp capping using either Biodentine, WMTA, or calcium hydroxide.
A total of 180 primary teeth from 9 healthy 4-month-old female pigs were divided into 3 experimental periods (7, 28, and 90 days) for each material used for the pulpotomy and direct pulp capping treatments. Seven, 28, and 90 days later, the animals were euthanized and the specimens were prepared for histological examination and evaluation. The data collected from the histological examinations were statistically analyzed using Kruskal-Wallis and Dunn multiple comparison tests.
In pulpotomy groups, there was a significant difference between Biodentine and WMTA vs FC in terms of inflammatory cell response and hard tissue formation. In direct pulp capping groups, there was only a significant difference between Biodentine and calcium hydroxide in terms of hard tissue formation in a 7-day period.
Biodentine and white mineral trioxide aggregate are both suitable, biocompatible materials for pulp capping in primary teeth of pigs.
本研究旨在评估和比较在猪乳牙中,使用生物陶瓷(一种新型硅酸三钙水门汀)、白色矿物三氧化物凝聚体(WMTA)或甲醛甲酚(FC)进行牙髓切断术后的牙髓反应,并在使用生物陶瓷、WMTA或氢氧化钙进行直接盖髓术后重复上述操作并比较。
从9只健康的4月龄雌性猪身上获取180颗乳牙,针对牙髓切断术和直接盖髓术所用的每种材料,将其分为3个实验阶段(7天、28天和90天)。7天、28天和90天后,对动物实施安乐死,并制备标本用于组织学检查和评估。使用Kruskal-Wallis和Dunn多重比较检验对组织学检查收集的数据进行统计分析。
在牙髓切断术组中,生物陶瓷和WMTA与FC相比,在炎症细胞反应和硬组织形成方面存在显著差异。在直接盖髓术组中,仅在7天的硬组织形成方面,生物陶瓷和氢氧化钙之间存在显著差异。
生物陶瓷和白色矿物三氧化物凝聚体都是适合用于猪乳牙盖髓的生物相容性材料。