Guérin A P, Marchais S J, Métivier F, London G M
Centre hospitalier FH Manhes, Fleury-Mérogis.
Rev Prat. 1990 Mar 1;40(7):625-9.
Coronary disease and left ventricular failure are the two main causes of death in haemodialysis patients. In these particular patients it is the accumulation of several risk factors rather than accelerated atherogenesis which seems to be the responsible for the frequent manifestations of a coronary disease which is sometimes difficult to diagnose. Independently of any cardiovascular history, the so-called "uraemic cardiopathy" is characterized by left ventricular dilatation associated with an increased myocardial mass but with a low mass/volume ratio. The systolic function is preserved whereas the ventricular diastolic compliance is altered due to the left ventricular hypertrophy.
冠状动脉疾病和左心室衰竭是血液透析患者的两大主要死因。在这些特殊患者中,似乎是多种危险因素的累积而非动脉粥样硬化加速,导致了冠状动脉疾病的频繁表现,而这种疾病有时难以诊断。无论有无心血管病史,所谓的“尿毒症性心肌病”的特征是左心室扩张,心肌质量增加,但质量/体积比降低。收缩功能得以保留,而由于左心室肥厚,心室舒张顺应性发生改变。