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[1例低位前切除术后局部复发性直肠癌病例报告,该病例对新辅助放化疗呈病理完全缓解]

[A case report of locally recurrent rectal cancer after low anterior resection that led to a pathological complete response to neoadjuvant chemoradiotherapy].

作者信息

Matsushita Ako, Takemoto Hiroyoshi, Ikeda Masataka, Munakata Tetsu, Fukunaga Mutsumi, Kawabata Ryohei, Yamamoto Tameyoshi, Oda Kazuyuki, Kishimoto Tomono, Imamura Hiroshi, Ohzato Hiroki

机构信息

Dept. of Surgery, Sakai City Hospital, Japan.

出版信息

Gan To Kagaku Ryoho. 2012 Nov;39(12):2261-3.

Abstract

We report a case of low anterior resection that led to a pathological complete response of locally recurrent rectal cancer to neoadjuvant chemoradiotherapy. A 57-year-old male patient underwent low anterior resection for rectal cancer pathologically diagnosed as type 2, tub2>tub1,pSS,INF b,int,ly2,v2,pPM0,pDM0,no,M0,H0,P0, and fStage II. After 2 years and 11 months, local recurrence of his rectal cancer was identified by colon fiberscopy. Neoadjuvant chemoradiotherapy was conducted with CPT-11, UFT/LV, and radiation(50 Gy),and this recurrent lesion exhibited a partial response to the chemoradiotherapy regimen according to magnetic resonance imaging findings. Then, we performed total pelvic exenteration, and the pathological examination revealed a pathological complete response.

摘要

我们报告了一例低位前切除术,该手术使局部复发性直肠癌对新辅助放化疗产生了病理完全缓解。一名57岁男性患者因直肠癌接受了低位前切除术,病理诊断为2型,tub2>tub1,pSS,INF b,int,ly2,v2,pPM0,pDM0,无,M0,H0,P0,f分期为II期。2年11个月后,通过结肠镜检查发现他的直肠癌局部复发。采用CPT-11、UFT/LV和放疗(50 Gy)进行新辅助放化疗,根据磁共振成像结果,该复发病变对放化疗方案表现出部分缓解。然后,我们进行了全盆腔脏器切除术,病理检查显示为病理完全缓解。

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