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扩大儿童复杂性阑尾炎的非手术治疗应用。

Expanded utilization of nonoperative management for complicated appendicitis in children.

机构信息

Division of Pediatric Surgery, Loma Linda University School of Medicine, 11175 Campus St, CP 21111, Loma Linda, CA 92354, USA.

出版信息

Langenbecks Arch Surg. 2013 Mar;398(3):463-6. doi: 10.1007/s00423-012-1042-5. Epub 2012 Dec 27.

Abstract

PURPOSE

The initial approach to complicated appendicitis in children has become increasingly nonoperative, particularly when there is presumed perforation and a localized abscess. We extended the indications for nonoperative management to include most cases other than simple appendicitis, including those with diffuse peritoneal involvement. We evaluated outcomes and sought to identify factors at the time of hospital admission that predicted an extended length of stay (LOS) with this strategy.

METHODS

The records of 223 consecutive children who were managed nonoperatively for complicated appendicitis were reviewed. A conservative approach was typically pursued in those with an abscess, phlegmon, or free fluid on initial imaging studies, and diffuse tenderness, diarrhea, or significant leukocytosis after 2 days of symptoms. Interval appendectomies were performed selectively.

RESULTS

The average LOS was 5.6 days (1-38), but nine subjects had a LOS of greater than 14 days. Eleven (4.9 %) required appendectomy during the initial admission. Free fluid on admission imaging studies, present in 78 % of those with an extended LOS, [odds ratio (OR) 5.5], in addition to a requirement for early nasogastric drainage (OR 24.2) and a higher band count (19 vs 15 %), was significantly associated with an extended LOS.

CONCLUSIONS

An expansion of the indications for nonoperative management of complicated appendicitis yielded an acceptable average LOS and a low incidence of early appendectomy. However, a small subset of subjects had an extended LOS, and most of those had free peritoneal fluid on admission.

摘要

目的

儿童复杂性阑尾炎的初始治疗方法已越来越倾向于非手术治疗,尤其是当存在穿孔和局部脓肿时。我们将非手术治疗的适应证扩展到包括大多数除单纯性阑尾炎以外的病例,包括那些有弥漫性腹膜受累的病例。我们评估了结果,并试图确定在入院时的哪些因素可以预测采用这种策略的住院时间延长。

方法

回顾了 223 例连续接受非手术治疗的复杂性阑尾炎患儿的记录。对于那些在初始影像学研究中出现脓肿、蜂窝织炎或游离液体的患者,以及在症状出现 2 天后出现弥漫性压痛、腹泻或显著白细胞增多的患者,通常采用保守治疗方法。间隔期行阑尾切除术。

结果

平均住院时间为 5.6 天(1-38 天),但有 9 名患者的住院时间超过 14 天。11 名(4.9%)患者在初次入院时需要行阑尾切除术。入院影像学检查显示有游离液体的患者,其延长住院时间的比例为 78%(比值比[OR] 5.5),此外,还需要早期行鼻胃管引流(OR 24.2)和更高的白细胞计数(19 vs 15%),与延长住院时间显著相关。

结论

扩大复杂性阑尾炎非手术治疗的适应证,可获得可接受的平均住院时间和较低的早期阑尾切除率。然而,仍有一小部分患者的住院时间延长,且大多数患者在入院时都有游离的腹膜液。

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