Zavras Nick, Vaos George
Department of Paediatric Surgery, "ATTIKON" University General Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens 12462, Greece.
World J Gastrointest Surg. 2020 Apr 27;12(4):129-137. doi: 10.4240/wjgs.v12.i4.129.
Complicated acute appendicitis (CAA) is a serious condition and carries significant morbidity in children. A strict diagnosis is challenging, as there are many lesions that mimic CAA. The management of CAA is still controversial. There are two options for treatment: Immediate operative management and non-operative management with antibiotics and/or drainage of any abscess or phlegmon. Each method of treatment has advantages and disadvantages. Operative management may be difficult due to the presence of inflamed tissues and may lead to detrimental events. In many cases, non-operative management with or without drainage and interval appendectomy is advised. The reasons for this approach include new medications and policies for the use of antibiotic therapy. Furthermore, advances in radiological interventions may overcome difficulties such as diagnosing and managing the complications of CAA without any surgeries. However, questions have been raised about the risk of recurrence, prolonged use of antibiotics, lengthened hospital stay and delay in returning to daily activities. Moreover, the need for interval appendectomy is currently under debate because of the low risk of recurrence. Due to the paucity of high-quality studies, more randomized controlled trials to determine the precise management strategy are needed. This review aims to study the current data on operative non-operative management for CAA in children and to extract any useful information from the literature.
复杂性急性阑尾炎(CAA)是一种严重疾病,在儿童中具有较高的发病率。由于存在许多类似CAA的病变,严格诊断具有挑战性。CAA的治疗仍存在争议。治疗有两种选择:立即手术治疗和使用抗生素及对任何脓肿或蜂窝织炎进行引流的非手术治疗。每种治疗方法都有优缺点。由于存在炎症组织,手术治疗可能困难,且可能导致不良事件。在许多情况下,建议采用带或不带引流的非手术治疗以及间隔期阑尾切除术。这种方法的原因包括新的药物和抗生素治疗政策。此外,放射介入技术的进步可能克服诸如无需任何手术即可诊断和处理CAA并发症等困难。然而,人们对复发风险、抗生素的长期使用、住院时间延长以及恢复日常活动延迟等问题提出了质疑。此外,由于复发风险较低,目前对于间隔期阑尾切除术的必要性存在争议。由于高质量研究匮乏,需要更多随机对照试验来确定精确的治疗策略。本综述旨在研究目前关于儿童CAA手术及非手术治疗的数据,并从文献中提取任何有用信息。