Site-specific inheritance of basal cell carcinoma.

We report a 21-year-old white woman who developed a large basal cell carcinoma (BCC) on her left upper vermilion border. Her mother and maternal grandmother both had a history of BCCs occurring in the same location. No documented BCC-related genetic disorder was suspected. Our case supports a theory of site-specific inheritance of nonmelanoma skin cancer, which should be further explored.