Yaghoobi Reza, Ranjbari Nastaran, Pazyar Nader, Foroozan Maryam, Feily Amir
Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Acta Med Indones. 2017 Jul;49(3):255-258.
Although basal cell carcinoma (BCC) is a common skin tumor, very rare cases of BCC arising from upper vermilion mucosa of lip have been reported previously. This tumor basically, originates from pillar structures and the involvement of the vermilion lip contrasts this concept so it is devoid of hair follicles and sweat glands. The exact pathogenesis of vermilion lip BCC is not clear but it has been postulated that the neoplasm originates from the pluripotential epithelial cells of the oral mucosa and epidermis. On the other hand, some authors consider their origin from ectopic sebaceous glands. Herein, we report a 34- year-old man with an asymptomatic ulcerated lesion on the upper left lip vermilion mucosa .The diagnosis of BCC was confirmed with histopathological examination after incisional biopsy of the mucosal neoplasm. After surgery of lip lesion, no recurrency was seen after 3 months follow-up the patient.
尽管基底细胞癌（BCC）是一种常见的皮肤肿瘤，但先前仅有极罕见的起源于唇部上唇红黏膜的基底细胞癌病例报道。这种肿瘤基本上起源于柱状结构，而上唇红受累与这一概念相悖，因为上唇红没有毛囊和汗腺。唇红部基底细胞癌的确切发病机制尚不清楚，但据推测该肿瘤起源于口腔黏膜和表皮的多能上皮细胞。另一方面，一些作者认为其起源于异位皮脂腺。在此，我们报告一名34岁男性，其左上唇红黏膜有一无症状溃疡性病变。对黏膜肿物进行切开活检后，经组织病理学检查确诊为基底细胞癌。唇部病变手术后，对患者进行3个月随访，未见复发。
