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[使用放电法消融希氏束的经验]

[Experience with ablation of the bundle of His using electrical discharge].

作者信息

Lukl J, Cernosek B, Heinc P

出版信息

Vnitr Lek. 1990 Jan;36(1):37-44.

PMID:2327082
Abstract

Ablation of the bundle of His by an electric discharge was made in 10 patients (average age 64 years, range 48-80) unsuccessfully treated with 3-14 antiarrhythmic drugs or their combinations (average 8.7) on account of supraventricular tachycardia occurring repeatedly for 3-44 years (average 12.5 years). By means of a bipolar electrode inserted into the area of the bundle of His a nonsynchronized defibrillation discharge with a mean energy of 323 J (40-380) was administered. On average 2.9 discharges were used (1-9) per patient, in 1-3 sessions. The patients were followed up for a period of 15.3 months (10-19). Permanent complete a-v block was achieved in 6 patients, the remaining 4 patients are also free from complaints with have antiarrhythmic treatment. To all patients a pacemaker was implanted, four times "physiological" stimulation was used. One month after the operation the authors observed once the development of a transient phatic disorder and once the slow development of cardiac tamponade in conjunction with anticoagulant treatment, resolved by pericardial puncture. Ablation of the bundle of His by a defibrillation discharge is thus in carefully selected patients a highly effective method of treatment of stubborn supraventricular tachycardias.

摘要

对10例(平均年龄64岁,范围48 - 80岁)因室上性心动过速反复发作3 - 44年(平均12.5年)而接受3 - 14种抗心律失常药物或其联合治疗(平均8.7种)但治疗失败的患者进行了希氏束电消融术。通过插入希氏束区域的双极电极给予平均能量为323焦耳(40 - 380焦耳)的非同步除颤放电。每位患者平均使用2.9次放电(1 - 9次),分1 - 3次进行。对患者进行了15.3个月(10 - 19个月)的随访。6例患者实现了永久性完全房室传导阻滞,其余4例患者在接受抗心律失常治疗后也无不适症状。所有患者均植入了起搏器,其中4次使用了“生理性”刺激。术后1个月,作者观察到1例出现短暂的淋巴管紊乱,1例在抗凝治疗过程中缓慢出现心包填塞,经心包穿刺后缓解。因此,对经过精心挑选的患者,通过除颤放电消融希氏束是治疗顽固性室上性心动过速的一种高效方法。

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