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[人体房室传导系统高频电消融的初步经验]

[Initial experiences with high-frequency electric ablation of the AV conduction system in the human].

作者信息

Budde T, Breithardt G, Borggrefe M, Podczeck A, Langwasser J

出版信息

Z Kardiol. 1987 Apr;76(4):204-10.

PMID:3604372
Abstract

For the first time, radiofrequency alternating current ablation of the AV-conduction system was performed in a 49-year-old female patient with recurrent atrial tachycardia with fast atrioventricular conduction, refractory to medical therapy, and two conventional DC-shock catheter ablation procedures. Without underlying cardiac disease, the patient had experienced almost daily episodes of tachycardia with a total of 10 syncopes. An electrophysiological study had revealed an ectopic right-atrial tachycardia and fast AV conduction up to a rate of more than 180 bpm. Soon after conventional right atrial catheter ablation, tachycardia with normal AV-conduction had recurred. Therefore, after catheter positioning (Lumelec, Cordis) at the proximal His bundle, 5 alternating current high-frequency pulses with an output energy of up to 50 W were applied under general anaesthesia. After the fourth application, the ECG revealed IIIrd degree AV-block with a His-bundle escape rhythm of 50 bpm. No complications occurred. Subsequent echocardiography did not reveal any pathological changes. The patient was put on anticoagulant therapy for the following 3 months and discharged after implantation of a permanent, activity-controlled pacemaker system (Activitrax, Medtronic). AV-block was persistent within a follow-up period of 3 months.

摘要

首次对一名49岁患有复发性房性心动过速且房室传导快速、药物治疗无效以及两次传统直流电休克导管消融术均无效的女性患者进行了房室传导系统的射频交流电消融。该患者无潜在心脏病,几乎每天都有心动过速发作,共发生10次晕厥。电生理研究显示为异位右房性心动过速且房室传导快速,心率超过180次/分钟。在传统右房导管消融术后不久,伴有正常房室传导的心动过速复发。因此,在将导管(Lumelec,Cordis)置于希氏束近端后,在全身麻醉下施加了5个输出能量高达50W的高频交流电脉冲。在施加第4次后,心电图显示三度房室传导阻滞,希氏束逸搏心律为50次/分钟。未发生并发症。随后的超声心动图未显示任何病理变化。患者在接下来的3个月接受抗凝治疗,并在植入永久性、活动控制型起搏器系统(Activitrax,美敦力)后出院。在3个月的随访期内,房室传导阻滞持续存在。

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