大鼠中枢神经系统富含突触体的组分中γ-氨基丁酸、甘氨酸和β-丙氨酸的高亲和力结合过程。
High-affinity binding processes for GABA, glycine, and beta-alanine in synaptosome-enriched fractions of rats CNS.
作者信息
De Feudis F V
出版信息
J Physiol (Paris). 1979;75(6):651-4.
PMID:232720
Abstract
A bicuculline-sensitive component of the binding of GABA and strychnine-sensitive components of the binding of glycine and beta alanine to synaptosome-enriched fractions of rat CNS have been demonstrated in the presence of physiological concentrations of Na+ and other inorganic ions. These processes might be related to synaptic receptors for these inhibitory amino-acids.
摘要
在生理浓度的钠离子和其他无机离子存在的情况下，已证实大鼠中枢神经系统富含突触体的组分中，γ-氨基丁酸（GABA）结合的荷包牡丹碱敏感成分以及甘氨酸和β-丙氨酸结合的士的宁敏感成分。这些过程可能与这些抑制性氨基酸的突触受体有关。
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