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局部麻醉与硬膜外麻醉在快速通道腹主动脉手术中的应用比较。

Local versus epidural anesthesia in fast-track abdominal aortic surgery.

机构信息

Department of Anaesthesia, University Hospital Maggiore della Carità, Novara, Italy.

出版信息

J Cardiothorac Vasc Anesth. 2013 Jun;27(3):451-8. doi: 10.1053/j.jvca.2012.09.026. Epub 2012 Dec 28.

Abstract

OBJECTIVE

The aim of this study was to investigate a possible alternative to epidural anesthesia/analgesia. The authors compared thoracic epidural anesthesia/analgesia with continuous wound infiltration anesthesia/analgesia in patients scheduled for mini-invasive abdominal aortic surgery in a fast-track setting.

DESIGN

A prospective randomized study.

SETTING

A university hospital.

PARTICIPANTS

Sixty patients undergoing fast-track abdominal aortic surgery.

INTERVENTIONS

The authors compared thoracic epidural infusion (the PERI group) with continuous local wound infiltration (the LOC group) for anesthesia/analgesia. Pain scores, the resumption of oral feeding, the resumption of ambulation, the day of discharge, and postoperative complications in the immediate (ie, 30 days) and long-term periods (ie, 2 years) were evaluated.

MEASUREMENTS AND MAIN RESULTS

Pain scores were low in both groups. The intraoperative LOC group needed higher doses of anesthetic/analgesic drugs. The postoperative LOC group needed significantly higher doses of bupivacaine (3.9 ± 0.7 mL/h [PERI group] and 5.7 ± 1.3 mL/h [LOC group] on day 0 [p < 0.01]; 3.8 ± 0.8 mL/h [PERI group] and 5.3 ± 1 mL/h [LOC group] on day 1 [p < 0.01]). The parameters of postoperative recovery were comparable between the 2 groups in terms of the resumption of ambulation after surgery (within 3 hours), feeding (within 6 hours), the passage of stools (mean 2 days), and the median hospital stay (3 days). In the 2-year follow-up period, a difference between the 2 groups in the incidence of wound complications was not observed.

CONCLUSIONS

The results obtained showed good and similar pain control in the 2 groups, but the LOC group required higher doses of anesthetic/analgesic drugs. Parameters of the postoperative recovery were similar in both groups.

摘要

目的

本研究旨在探讨硬膜外麻醉/镇痛的一种可能替代方法。作者在快速通道条件下比较了微创腹主动脉手术患者的胸硬膜外麻醉/镇痛与连续切口浸润麻醉/镇痛。

设计

前瞻性随机研究。

地点

一家大学医院。

参与者

60 例行快速通道腹主动脉手术的患者。

干预措施

作者比较了胸硬膜外输注(PERI 组)与连续局部伤口浸润(LOC 组)在麻醉/镇痛方面的效果。评估了疼痛评分、恢复口服喂养、恢复活动、出院日期以及术后即刻(即 30 天)和长期(即 2 年)的并发症。

测量和主要结果

两组的疼痛评分均较低。术中 LOC 组需要更高剂量的麻醉/镇痛药物。术后 LOC 组需要显著更高剂量的布比卡因(第 0 天 PERI 组 3.9±0.7mL/h,LOC 组 5.7±1.3mL/h[P<0.01];第 1 天 PERI 组 3.8±0.8mL/h,LOC 组 5.3±1.0mL/h[P<0.01])。在术后恢复方面,两组在术后活动(3 小时内)、进食(6 小时内)、排便(平均 2 天)和中位住院时间(3 天)方面的参数相似。在 2 年随访期间,两组之间在伤口并发症的发生率方面没有差异。

结论

研究结果显示两组均能获得良好且相似的疼痛控制,但 LOC 组需要更高剂量的麻醉/镇痛药物。两组的术后恢复参数相似。

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