Stein M B, Tancer M E, Gelernter C S, Vittone B J, Uhde T W
Section on Anxiety and Affective Disorders, National Institute of Mental Health, Bethesda, MD 20892.
Am J Psychiatry. 1990 May;147(5):637-9. doi: 10.1176/ajp.147.5.637.
The authors examined the longitudinal course of affective illness retrospectively in 63 patients with social phobia and 54 patients with panic disorder. Significantly fewer (35%) of the patients with social phobia than patients with panic disorder (63%) had experienced at least one major depressive episode. Patients with generalized social phobia and patients with specific social phobia had comparable past rates of major depression (37% and 30%, respectively). The clinical and theoretical implications of these findings are discussed within the context of current concepts regarding the development of depressive symptoms in patients with anxiety disorders.