Correspondence should be addressed to Barbara Cherry, Department of Psychology, California State University, Fullerton, P.O. Box 6846, Fullerton, CA 92834-6846. E-mail:
J Gerontol B Psychol Sci Soc Sci. 2014 Mar;69(2):199-208. doi: 10.1093/geronb/gbs122. Epub 2012 Dec 28.
Persons with fibromyalgia (FM) report having cognitive dysfunction. Neuropsychological performance was compared across a variety of domains in 43 women with FM (Mage = 63 years) and in 44 women without FM (Mage = 65 years).
Measures included explicit memory (Consortium to Establish a Registry for Alzheimer's Disease [CERAD] immediate/delayed recall, delayed recognition), aspects of executive function including interference/inhibition (Stroop Color/Word test), working memory (Digit Span Forward/Backward), set-shifting/complex sequencing (Trails B), monitoring (verbal fluency: naming animals), processing speed (Trails A, Digit Symbol Substitution Coding), and problem solving (Everyday Problems Test).
Women with FM performed more poorly than controls on executive function (Stroop Color/Word) and one processing speed measure (Digit Symbol Substitution Coding).
Results partly support altered cognitive function in FM. Mixed findings across cognitive domains among individuals with or without FM is consistent with the literature and suggest that factors beyond those typically controlled for (e.g., heterogeneity in FM) may be influencing findings. Future research is warranted.
纤维肌痛(FM)患者报告存在认知功能障碍。在 43 名 FM 女性(平均年龄=63 岁)和 44 名无 FM 女性(平均年龄=65 岁)中比较了各种领域的神经心理学表现。
测量包括外显记忆(阿尔茨海默病建立登记册联合会 [CERAD] 即时/延迟回忆、延迟识别)、包括干扰/抑制(Stroop 颜色/文字测试)在内的执行功能的各个方面、工作记忆(数字跨度正向/反向)、转换/复杂序列(Trails B)、监测(言语流畅性:命名动物)、处理速度(Trails A、数字符号替代编码)和解决问题(日常问题测试)。
FM 女性在执行功能(Stroop 颜色/文字)和一项处理速度测量(数字符号替代编码)方面的表现均不如对照组。
结果部分支持 FM 中的认知功能改变。有或没有 FM 的个体在认知领域的混合发现与文献一致,表明除了那些通常控制的因素(例如,FM 的异质性)之外,可能还有其他因素影响研究结果。需要进一步的研究。