Werber D, Stark K
Fachgebiet für gastroenterologische Infektionen, Zoonosen und tropische Infektionen, Abteilung für Infektionsepidemiologie, Robert Koch-Institut, DGZ-Ring 1, 13086, Berlin, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Jan;56(1):38-41. doi: 10.1007/s00103-012-1591-3.
Timely outbreak detection is a major objective of the surveillance of food-borne infections. In this regard molecular subtyping is a very useful tool for several bacterial pathogens, e.g. enterohemorrhagic E. coli (EHEC), Listeria monocytogenes and various serotypes of non-typhoidal Salmonella. The basis is the characterization of patient isolates by molecular methods, preferably at the clonal level. The goal is to find groups of identical isolates which may indicate that they share a common origin, i.e. they might belong to an outbreak. In this article we put forward strong reasons why a systematic nationwide molecular subtyping surveillance is needed for selected bacterial pathogens in Germany.
及时发现疫情是食源性感染监测的主要目标。在这方面,分子分型对于几种细菌病原体来说是一种非常有用的工具,例如肠出血性大肠杆菌(EHEC)、单核细胞增生李斯特菌和各种非伤寒沙门氏菌血清型。其基础是通过分子方法对患者分离株进行特征分析,最好是在克隆水平上。目标是找到相同分离株的群体,这可能表明它们有共同的起源,即它们可能属于一次疫情。在本文中,我们提出了强有力的理由,说明德国为何需要对选定的细菌病原体进行全国性的系统分子分型监测。