Popoviciu L, Corfariu O, Földes A, Farkas E, Goldstein R, Pavel S
Waking Sleeping. 1979 Sep-Dec;3(4):341-6.
The lumbar cerebrospinal fluid (CSF) collected from 6 narcoleptic patients (three males and three females) aged between 31 and 47 years, as well as from 2 patients having Pickwickian syndromes with hypersomnia attacks (two males), aged 43-51 years, contained relatively high amounts of arginine vasotocin (AVT) only if the CSF was removed after a REM sleep period. The release was not induced by darkness since the same release of AVT occurred when the CSF was removed after a REM sleep period during daylight hours. No detectable AVT levels have been found in the CSF samples of four narcoleptics collected after a NREM period of sleep, either during night or daylight hours. The present results suggest a possible alteration of the rhythmical release of AVT both in narcolepsy and in narcoleptic syndromes.
从6名年龄在31至47岁之间的发作性睡病患者（3名男性和3名女性）以及2名患有匹克威克综合征且有发作性嗜睡症的患者（2名男性，年龄在43至51岁之间）采集的腰椎脑脊液（CSF），只有在快速眼动睡眠期后采集时，才含有相对较高量的精氨酸血管加压素（AVT）。这种释放不是由黑暗诱导的，因为在白天快速眼动睡眠期后采集脑脊液时，AVT会发生相同的释放。在非快速眼动睡眠期后采集的4名发作性睡病患者的脑脊液样本中，无论是在夜间还是白天，均未检测到可检测到的AVT水平。目前的结果表明，发作性睡病和发作性睡病综合征中AVT的节律性释放可能存在改变。
