Children's Hospital Oakland Research Institute, Oakland, CA, USA.
Int J Immunogenet. 2013 Feb;40(1):39-45. doi: 10.1111/iji.12028. Epub 2012 Dec 26.
In the last fifteen years, published reports have described KIR gene-content frequency distributions in more than 120 populations worldwide. However, there have been limited studies examining these data in aggregate to detect overall patterns of variation at regional and global levels. Here, we present a summary of the collection of KIR gene-content data for 105 worldwide populations collected as part of the 15th and 16th International Histocompatibility and Immunogenetics Workshops, and preliminary results for data analysis.
在过去的十五年中,已有超过 120 个国家和地区的发表报告描述了 KIR 基因含量的频率分布。然而,对这些数据进行总体评估以检测区域和全球水平的总体变化模式的研究是有限的。在这里,我们总结了第 15 和 16 届国际组织相容性和免疫遗传学研讨会收集的来自全球 105 个群体的 KIR 基因含量数据,并对数据分析的初步结果进行了介绍。