Laboratoire de RMN en Milieu Orienté, ICMMO, UMR CNRS 8182, Bât 410, Université Paris-Sud, 91405 Orsay cedex, France.
Magn Reson Chem. 2012 Dec;50 Suppl 1:S12-6. doi: 10.1002/mrc.3857.
It is demonstrated that (2)H NMR in chiral liquid crystalline solvents can be used to measure enantiomeric excesses using exchangeable deuterons in alcohols. This is performed in a trivial way at low temperature (260-270 K) where a slow exchange regime was reached. Among the various alcohols used to explore the possibilities of this technique, an unusually large isotopic effect on molecular orientation between two isotopomers has been observed.
研究表明，在手性液晶溶剂中的（2）H NMR 可用于测量醇类中可交换的氘的对映过量。在低温（260-270 K）下，通过达到缓慢交换的状态，可以以简单的方式进行操作。在所使用的各种醇中，研究了该技术的可能性，观察到两个同位素之间的分子取向的同位素效应异常大。
