Barber A M, Maizel J V
Laboratory of Mathematical Biology, National Cancer Institute, Frederick, MD 21701-1013.
Genet Anal Tech Appl. 1990 Apr;7(2):39-45. doi: 10.1016/0735-0651(90)90011-4.
Here we present the SequenceEditingAligner system for editing multiple, aligned genetic sequences. This is an interactive multi-window color system that displays more than 3500 nucleotides or amino acids. The system handles nucleic acid or protein sequences with or without secondary structure data. More than 300 sequences, each more than 1500 elements in length, may be analyzed together. With the system scientists can classify elements, align sequences, edit them, find consensus patterns, and simultaneously generate oligomer frequency histograms and other statistics.
在此,我们展示了用于编辑多个比对的基因序列的序列编辑比对系统。这是一个交互式多窗口颜色系统,可显示超过3500个核苷酸或氨基酸。该系统可处理带有或不带有二级结构数据的核酸或蛋白质序列。可以一起分析300多个序列,每个序列长度超过1500个元素。借助该系统,科学家可以对元素进行分类、比对序列、编辑序列、找到共有模式,并同时生成寡聚物频率直方图和其他统计数据。