Luckow V A, Littlewood R K, Rownd R H
Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):665-73. doi: 10.1093/nar/12.1part2.665.
A group of interactive computer programs have been developed which aid in the collection and graphical analysis of nucleotide and protein sequence data. The programs perform the following basic functions: a) enter, edit, list, and rearrange sequence data; b) permit automatic entry of nucleotide sequence data directly from an autoradiograph into the computer; c) search for restriction sites or other specified patterns and plot a linear or circular restriction map, or print their locations; d) plot base composition; e) analyze homology between sequences by plotting a two-dimensional graphic matrix; and f) aid in plotting predicted secondary structures of RNA molecules.
已经开发出一组交互式计算机程序,可协助进行核苷酸和蛋白质序列数据的收集及图形分析。这些程序执行以下基本功能:a)输入、编辑、列出和重新排列序列数据;b)允许将核苷酸序列数据直接从放射自显影片自动输入计算机;c)搜索限制性酶切位点或其他特定模式,并绘制线性或环状限制性图谱,或打印其位置;d)绘制碱基组成;e)通过绘制二维图形矩阵分析序列之间的同源性;f)协助绘制RNA分子的预测二级结构。