Ortiz-Vázquez Iraís Cristal, Ramos-García Marco Antonio, Maza-Juárez Gerardo, Clavellina-Rosas Juan Marcelino, Moreno-Vázquez Alejandra, Calderón-Abbo Moisés
Hospital de Cardiología, Centro Médico Nacional Siglo XXI,Instituto Mexicano del Seguro Social, Distrito Federal, México.
Rev Med Inst Mex Seguro Soc. 2012 Sep-Oct;50(5):559-63.
pheochromocytoma is a neuroendocrine tumor that secretes high levels of catecholamines and it is able to exert serious cardiovascular effects. The cardiac involvement is the most frequent, with reported conditions such as transient myocardial dysfunction, acute coronary syndrome and ventricular arrhythmias.
we reported a 36 year-old woman without cardiovascular history. She presented with an adrenergic crisis after surgery leading to acute heart failure and acute myocardial infarction. The electrocardiogram showed an ST-segment elevation and positive enzymatic curve, motion alterations in echocardiography and ventriculography without coronary arteries lesions. She was screened for secondary hypertension protocol with a 24 hour urine free catecholamine sample that was clearly elevated. Abdomen computed tomography and magnetic resonance imaging showed a tumor located in the right adrenal gland and she underwent surgical resection.
pheochromocytoma has different clinical presentations that may delay the diagnosis. Early recognition of catecholamine-induced cardiomyopathy and adequate management reduces morbidity and mortality.
嗜铬细胞瘤是一种分泌高水平儿茶酚胺的神经内分泌肿瘤，可产生严重的心血管效应。心脏受累最为常见，报道的情况有短暂性心肌功能障碍、急性冠状动脉综合征和室性心律失常等。
我们报告了一名36岁无心血管病史的女性。她术后出现肾上腺素能危象，导致急性心力衰竭和急性心肌梗死。心电图显示ST段抬高和酶学曲线阳性，超声心动图和心室造影显示运动改变，冠状动脉无病变。通过24小时尿游离儿茶酚胺样本进行继发性高血压筛查，结果明显升高。腹部计算机断层扫描和磁共振成像显示肿瘤位于右肾上腺，她接受了手术切除。
嗜铬细胞瘤有不同的临床表现，可能会延迟诊断。早期识别儿茶酚胺诱导的心肌病并进行适当治疗可降低发病率和死亡率。
