Eduardo Fernanda de Paula, Bezinelli Letícia Mello, Hamerschlak Nelson, Andrade Claudia Toledo, Morelli Leonardo Raul, Corrêa Luciana
Bone Marrow Transplant Center, Hospital Israelita Albert Einstein, São Paulo (SP), Brazil.
Rev Bras Hematol Hemoter. 2011;33(1):15-20. doi: 10.5581/1516-8484.20110008.
Oral care is a fundamental procedure for the success of the hematopoietic stem cell transplantation, particularly regarding the control of oral infectious diseases. Information about oral care protocols and the inclusion of dental professionals in transplantation medical staff is poorly known.
The aim of this study was to carry out a survey about the protocols of Brazilian dental professionals with regard to oral care of HSCT patients.
A questionnaire was mailed to 36 Brazilian transplant centers with questions about basic oral care protocols, the indication of specific mouthwashes, antibiotic therapy regimens, laser therapy, and treatment of oral mucositis and graft-versus-host disease. All the respondent centers (n = 12) have dentists as members of the HSCT medical staff.
The majority indicate non-alcoholic chlorhexidine (n = 9; 75.0%) and sodium bicarbonate (n = 5; 41.7%) as routine mouthwashes. Laser therapy was frequently indicated (n= 9; 75.0%), mainly in the prevention of oral mucositis and in oral pain control. In the post-transplant period, antibiotic therapy was only indicated for invasive dental treatments (n= 8; 66.7%). Several treatments for graft-versus-host disease were mentioned without a trend towards establishing a standard protocol.
Basic oral care constitutes regular assessment in the routine treatment of hematopoietic stem cell transplantation patients in Brazilian centers.
口腔护理是造血干细胞移植成功的一项基本程序,尤其是在控制口腔传染病方面。关于口腔护理方案以及牙科专业人员纳入移植医护人员队伍的信息鲜为人知。
本研究的目的是对巴西牙科专业人员关于造血干细胞移植患者口腔护理的方案进行一项调查。
向36个巴西移植中心邮寄了一份问卷,问题涉及基本口腔护理方案、特定漱口水的使用指征、抗生素治疗方案、激光治疗以及口腔黏膜炎和移植物抗宿主病的治疗。所有回复的中心(n = 12)都有牙医作为造血干细胞移植医护人员的成员。
大多数中心指出非酒精性氯己定(n = 9;75.0%)和碳酸氢钠(n = 5;41.7%)作为常规漱口水。经常提到激光治疗(n = 9;75.0%),主要用于预防口腔黏膜炎和控制口腔疼痛。在移植后时期,抗生素治疗仅用于侵入性牙科治疗(n = 8;66.7%)。提到了几种移植物抗宿主病的治疗方法,但没有建立标准方案的趋势。
在巴西各中心,基本口腔护理是造血干细胞移植患者常规治疗中的定期评估内容。