Spinelli D, DE Vico G, Bonino M, Barlattani A, Bollero P, Barlattani A
University of Rome "Tor Vergata", School of Dentistry, President: Prof. A. Barlattani.
Oral Implantol (Rome). 2009 Oct;2(4):26-34. Epub 2010 May 25.
The osteonecrosis of the maxillares caused by bisphosphonates (OMB) either wrongly known or not reconised in earlier times became nowadays very important among the dentists and maxillo-facials surgeons because of the potential serious consequences that might bring in the oral cave of the patients, who are suffering already for their base condition. The goal of our work was to verify if a deep treatment and an attentive observation with a close follow-up can bring to the resolution of serious cases of ostenecrosis of the maxillares by bisphosphonantes. Although without a statistic value our case report put the basis for a chance to execute wider casistic studies.
双膦酸盐导致的上颌骨坏死（OMB），在早期要么未被正确认识，要么未被识别，如今在牙医和颌面外科医生中变得非常重要，因为它可能给已经因基础疾病而痛苦的患者口腔带来潜在的严重后果。我们研究的目的是验证深度治疗和密切随访的仔细观察是否能使双膦酸盐导致的严重上颌骨坏死病例得到解决。尽管我们的病例报告没有统计学价值，但它为进行更广泛的病例研究提供了机会。
