Nigam Jitendra Singh, Misra Vatsala, Singh Anshul, Karuna Veer, Chauhan Smita
Junior resident, Department of Pathology, M.L.N.Medical College Allahabad, U.P., India.
J Clin Diagn Res. 2012 Nov;6(9):1559-61. doi: 10.7860/JCDR/2012/4233.2561.
A 45 year old male patient presented with the complaint of a purplish nodular painful swelling on the flexor aspect of the left forearm of five years duration. A radiological examination of the lesion was not done prior to its excision. A biopsy was done and it was sent for a histopathological examination. The biopsied tissue was single, irregular, firm and globular, it measured 0.5 x 0.5cm in size and it was processed in two halves Its microscopic examination showed a well circumscribed area which comprised of sheets and nodules of monomorphic round cells with slightly vesicular, round nuclei and an acidophilic cytoplasm, amongst which were interspersed numerous blood vessels, many of which were dilated and congested, along with numerous lymphatic channels which were filled with lymph. Immunohistochemistry for SMA, CEA and CD 34 was advised, out of which only SMA turned out to be strongly positive and a final diagnosis of a Glomus tumour was made.
一名45岁男性患者，主诉左前臂屈侧有一个紫色结节状疼痛性肿物，病程5年。在切除该病变之前未进行影像学检查。进行了活检并送去做组织病理学检查。活检组织为单个、不规则、质地硬且呈球状，大小为0.5×0.5厘米，分成两半进行处理。显微镜检查显示一个边界清楚的区域，由单形性圆形细胞的片状和结节状结构组成，细胞核稍呈泡状、圆形，细胞质嗜酸性，其中散布着许多血管，许多血管扩张且充血，还有许多充满淋巴液的淋巴管。建议对平滑肌肌动蛋白（SMA）、癌胚抗原（CEA）和CD 34进行免疫组织化学检查，结果只有SMA呈强阳性，最终诊断为血管球瘤。
