Googe P B, Griffin W C
Department of Pathology, University of Tennessee Medical Center, Knoxville 37920.
J Cutan Pathol. 1993 Aug;20(4):359-63. doi: 10.1111/j.1600-0560.1993.tb01276.x.
An intravenous glomus tumor occurring in a forearm vein is reported. The patient had a painful subcutaneous mass which was completely excised. This mass was a neoplasm which expanded the lumen of a vein and extended throughout its wall into the surrounding subcutaneous fat. The neoplasm consisted of sheets of rounded cells with a capillary stroma. The neoplastic cells were closely apposed to the capillary vessels and were positive for vimentin, smooth muscle actin and muscle specific actin. The cells were negative for desmin, factor VIII-related antigen, epithelial membrane antigen, cytokeratins, S-100 protein and chromogranin. This is the 2nd reported case of intravenous glomus tumor of the forearm. This unusual presentation may be due to intravascular extension by a cutaneous glomus tumor. The potential for intravascular growth by glomus tumor should be recognized by surgeons, dermatologists and pathologists.
报告了一例发生在前臂静脉的静脉内血管球瘤。患者有一个疼痛的皮下肿块，已被完全切除。该肿块是一种肿瘤，它使静脉腔扩大，并穿过静脉壁延伸至周围皮下脂肪。肿瘤由成片的圆形细胞和毛细血管间质组成。肿瘤细胞紧密贴附于毛细血管，波形蛋白、平滑肌肌动蛋白和肌肉特异性肌动蛋白呈阳性。细胞结蛋白、因子VIII相关抗原、上皮膜抗原、细胞角蛋白、S-100蛋白和嗜铬粒蛋白呈阴性。这是第二例报告的前臂静脉内血管球瘤。这种不寻常的表现可能是由于皮肤血管球瘤向血管内扩展所致。外科医生、皮肤科医生和病理学家应认识到血管球瘤血管内生长的可能性。
