Shilov V V, Andriaov A Yu, Loladze A T, Batotsyrenov B V
Klin Med (Mosk). 2012;90(10):24-7.
We studied the development of metabolic disorders related to tissue hypoxia in 54 patients with acute severe asaleptin intoxication complicated by acute respiratory insfficiency of mixed genesis. We also estimated the role of a substrate antihypoxant cytoflavin in the correction of these disorders and clinical features of acute intoxication. Cyroflavin was shown to accelerate normalization of metabolic disorders which in turn improves clinical symptoms of severe forms of acute asaleptin intoxication.
我们研究了54例急性重度阿萨普汀中毒并发混合性急性呼吸功能不全患者中与组织缺氧相关的代谢紊乱的发展情况。我们还评估了底物抗缺氧剂细胞黄素在纠正这些紊乱以及急性中毒临床特征方面的作用。结果显示,细胞黄素可加速代谢紊乱的正常化,进而改善急性重度阿萨普汀中毒严重形式的临床症状。