心脏组织中折返的计算机模型。

A computer model of re-entry in cardiac tissue.

作者信息

Bailie A H, Mitchell R H, Anderson J M

机构信息

Department of Electrical & Electronic Engineering, University of Ulster, Newtownabbey, Northern Ireland.

出版信息

Comput Biol Med. 1990;20(1):47-54. doi: 10.1016/0010-4825(90)90043-o.

DOI:10.1016/0010-4825(90)90043-o

PMID:2328577

Abstract

This paper describes the use of a computer model to investigate the nature of impulse propagation and the mechanisms of electrical instability which precipitate ventricular arrhythmias. The model provides the opportunity for a systematic analysis of the conditions of cardiac conduction under controlled conditions. From the simulation studies performed it is found that the most critical parameter which influences re-entry circuit formation is the ratio of exited to refractory duration.

摘要

本文描述了使用计算机模型来研究冲动传播的本质以及引发室性心律失常的电不稳定机制。该模型为在可控条件下系统分析心脏传导状况提供了契机。从所进行的模拟研究中发现，影响折返环路形成的最关键参数是有效不应期与动作电位时程的比值。