Pérez de los Cobos J C, Jorda L L, Pelegrin C
Hospital Ramòn y Cajal, Servicio de Psiquiatria, Madrid, Espagne.
Encephale. 1990 Jan-Feb;16(1):41-2.
We relate a case of amineptine (Survector) dependence in a patient with a previous history of amphetamine dependence. Under pressure from the family, she came to the hospital with anxiety symptoms which had appeared 48 hours after suspension of the treatment. The product was initially prescribed by a psychiatrist three years previously and she took a dose of 100 mg/day for three months. Approximately one year ago she re-started the treatment on her own initiative, increasing the dose to about 30 tablets/day (3 g) in order to combat against asthenia and to be able to maintain her normal level of activity. In her history we find an episode of amphetamine dependence at 17 years old. We compare the characteristics of this case with other reported cases. Finally some recommendations for a better use of this antidepressant in similar cases are suggested.
我们讲述了一例既往有苯丙胺依赖史患者出现安非他明(Survector)依赖的病例。在家人的压力下,她因停药48小时后出现的焦虑症状前来医院就诊。该药物最初由一名精神科医生于三年前开具,她服用了三个月,剂量为每日100毫克。大约一年前,她自行重新开始治疗,将剂量增加至约每日30片(3克),以对抗乏力并维持正常活动水平。在她的病史中,我们发现她17岁时曾有过一次苯丙胺依赖发作。我们将该病例的特征与其他已报道的病例进行了比较。最后,针对在类似病例中更好地使用这种抗抑郁药提出了一些建议。