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沙特婴儿和儿童腹泻住院患者中溶组织内阿米巴感染的流行情况和特征:在吉达南部 2 家主要医院的一种再出现的严重感染,表现不典型。

Prevalence and characters of Entamoeba histolytica infection in Saudi infants and children admitted with diarrhea at 2 main hospitals at South Jeddah: a re-emerging serious infection with unusual presentation.

机构信息

Department of Pediatric, Mansoura University Children's Hospital, Infectious Diseases Unit, Mansoura, Egypt.

出版信息

Braz J Infect Dis. 2013 Jan-Feb;17(1):32-40. doi: 10.1016/j.bjid.2012.08.021. Epub 2013 Jan 1.

DOI:10.1016/j.bjid.2012.08.021
PMID:23287546
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9427352/
Abstract

In this study, Entamoeba histolytica had high prevalence and unusual presentation by affecting high proportion of infants under 1 year; severe clinical manifestations, and laboratory findings that were known to be usually encountered in invasive amebiasis as significant leukocytosis for age, neutrophilic leukocytosis for age, and positive C-reactive protein were found among more than 50% of admitted Saudi infants and children with E. histolytica infection in our locality. E. histolytica can be a re-emerging serious infection when it finds favorable environmental conditions and host factors which are mainly attributed to inadequate breastfeeding in this study. This may occur in any other area of the world with the same risk factors, so we must be ready to tackle it with effective and more powerful preventive measures.

摘要

在这项研究中,溶组织内阿米巴的流行率很高,表现也不寻常,影响了很大比例的 1 岁以下婴儿;严重的临床表现和实验室发现,在我们当地,超过 50%的患有溶组织内阿米巴感染的沙特住院婴儿和儿童中,年龄相关性显著白细胞增多、年龄相关性中性粒细胞增多和 C 反应蛋白阳性,这些都是侵袭性阿米巴病中常见的表现。当溶组织内阿米巴发现有利的环境条件和宿主因素时,它可能成为一种重新出现的严重感染,而在本研究中,主要归因于母乳喂养不足。在世界上任何其他存在相同危险因素的地区都可能发生这种情况,因此我们必须准备好采取有效和更有力的预防措施来应对它。

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