Korkhov V V, Sulukhiia R V, Makusheva V P, Mats M N
Farmakol Toksikol. 1990 Jan-Feb;53(1):50-1.
The results of experimental pharmacological studies may help obstetricians to make a choice of a schedule of using the uterotropic drugs and their doses. In vivo and in vitro experiments on pregnant rats showed that administration of the Soviet-made prostaglandin E2--prostenon--in combination with oxytocin and obsidan in half doses increased its stimulating effect on the myometrium. The use of prostenon and oxytocin against the background of partusisten treatment was not followed by a significant change of their stimulating uterotropic action.
实验药理学研究结果可能有助于产科医生选择宫缩剂的使用方案及其剂量。对妊娠大鼠进行的体内和体外实验表明，将苏联产的前列腺素E2（普罗斯托农）与缩宫素及半量的奥布西丹联合使用，可增强其对子宫肌层的刺激作用。在使用帕图西斯坦治疗的背景下使用普罗斯托农和缩宫素，其促子宫收缩作用未发生显著变化。
