Parida Pradipta Kumar
Department of Otorhinolaryngology and Head and Neck Surgery, JIPMER, Dhanvantri Nagar, Puducherry, Pin-605006, India.
Ear Nose Throat J. 2012 Nov;91(11):E11-6. doi: 10.1177/014556131209101113.
The paranasal sinuses are a rare location for metastases. The most frequent infraclavicular primary tumor to metastasize to the nose and paranasal sinuses is renal cell carcinoma. Three cases of bilateral renal cell carcinoma with metastases to the paranasal sinuses and with destruction of the skull base are reported. These patients had a primary renal cell carcinoma on the left side for which they had undergone a left nephrectomy many years previously. Right-sided renal cell carcinoma was diagnosed only after the patients had developed symptoms secondary to their metastases. These patients presented with the unusual manifestations of frontal swelling, proptosis, and epistaxis. They were offered palliative treatment in the form of radiotherapy and interferon therapy.
鼻窦是转移瘤的罕见部位。最常转移至鼻和鼻窦的锁骨下原发性肿瘤是肾细胞癌。本文报告了3例双侧肾细胞癌转移至鼻窦并破坏颅底的病例。这些患者左侧曾患原发性肾细胞癌，多年前已接受左肾切除术。仅在患者出现转移继发症状后才诊断出右侧肾细胞癌。这些患者表现出前额肿胀、眼球突出和鼻出血等不寻常症状。他们接受了放疗和干扰素治疗等姑息治疗。
