Shirani Amir Mansour
Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Isfahan University of Medical Sciences, Iran.
J Dent Res Dent Clin Dent Prospects. 2008 Spring;2(2):68-70. doi: 10.5681/joddd.2008.014. Epub 2008 Aug 15.
Lipoid proteinosis is a rare hereditary metabolic disorder transmitted as an autosomal recessive trait. It is characterized by the deposition of an amorphous hyaline-like material (glycoprotein) in the mucous membranes, skin and various internal organs. Cryosurgery (N(2)O) was applied to remove and reshape the lip lesions in a case of this rare syndrome. The patient was a 24-year-old female. Cryosurgery (-63ºC N(2)O for one minute) was performed to re-shape some areas of the upper lip. The lips were softer and had better esthetics after treatment. The use of cryosurgery offers advantages over surgery in reshaping of the lip lesions in this syndrome, since suturing is not feasible in rigid mucosa of these patients.
类脂蛋白沉积症是一种罕见的遗传性代谢紊乱疾病，以常染色体隐性性状遗传。其特征是一种无定形的透明样物质（糖蛋白）沉积于黏膜、皮肤及各种内脏器官。在一例这种罕见综合征患者中，应用冷冻手术（N₂O）切除并重塑唇部病变。患者为一名24岁女性。对其上唇部分区域进行了冷冻手术（-63℃ N₂O，持续1分钟）以重塑外形。治疗后唇部更柔软，美观度更佳。在该综合征唇部病变的重塑中，冷冻手术比手术具有优势，因为对这些患者的僵硬黏膜进行缝合是不可行的。
