Department of Oral and Maxillofacial Surgery (Head: Prof. C. Alexandridis), Dental School at "A. & P. Kyriakou Children's Hospital" (Director: Prof. I. Iatrou), University of Athens, Greece.
J Craniomaxillofac Surg. 2013 Oct;41(7):574-80. doi: 10.1016/j.jcms.2012.11.029. Epub 2013 Jan 2.
Fibro-osseous lesions, a diverse group of bone disorders including developmental, reactive or dysplastic diseases and neoplasms, share overlapping clinical, radiographic and histopathologic features and demonstrate a wide range of biological behaviour.
To evaluate the characteristics, treatment and outcome of benign fibro-osseous lesions of the jaws in children.
All patients with fibro-osseous lesions of the jaws treated at the department of Oral and Maxillofacial Surgery of the «A & P Kyriakou» Children's Hospital of Athens from 2000 to 2011 were included in this study. Data were retrieved from patients' files and their present situation was registered.
Sixteen males and 10 females (mean age 8.5 years) were treated. Fibrous dysplasia was most often encountered (26.9%), and the mandible was the most frequent location (76.9%). All cases were surgically treated and histopathologically confirmed. Marginal ostectomy was performed in 7 cases, partial ostectomy in 4, enucleation and curettage in 10 and trimming-remodelling in 5 cases. Mean follow-up was of 5.5 years with no recurrence, except in one case of fibrous dysplasia.
Fibro-osseous lesions, although sharing similar microscopic features, exhibit a variety of clinical behaviour rendering their treatment highly individualized.
纤维骨性病变是一组多样化的骨疾病,包括发育性、反应性或发育不良性疾病以及肿瘤,它们具有重叠的临床、影像学和组织病理学特征,并表现出广泛的生物学行为。
评估儿童颌骨良性纤维骨性病变的特征、治疗和结局。
本研究纳入了 2000 年至 2011 年期间在雅典“A & P Kyriakou”儿童医院口腔颌面外科治疗的所有颌骨纤维骨性病变患者。从患者的档案中检索数据,并记录其现状。
16 名男性和 10 名女性(平均年龄 8.5 岁)接受了治疗。纤维结构不良最为常见(26.9%),下颌骨是最常见的发病部位(76.9%)。所有病例均经手术治疗并经组织病理学证实。7 例行边缘性颌骨切除术,4 例行部分颌骨切除术,10 例行剜除和刮除术,5 例行修整-重塑术。平均随访 5.5 年,除 1 例纤维结构不良外,无复发。
纤维骨性病变虽然具有相似的显微镜下特征,但表现出多种临床行为,使其治疗具有高度的个体化。