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良性纤维-骨病变:口腔诊断环境中诊断的 143 例病例的临床病理特征。

Benign fibro-osseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting.

机构信息

Stomatology Service, Brazilian Dental Association, Rio de Janeiro, Brazil.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 May;115(5):e56-65. doi: 10.1016/j.oooo.2012.05.022. Epub 2012 Sep 13.

DOI:10.1016/j.oooo.2012.05.022
PMID:22981804
Abstract

OBJECTIVE

The aim of this study was to report the clinicopathologic and radiologic features of 143 benign fibro-osseous lesions (BFOLs).

STUDY DESIGN

Clinical and radiologic information were retrieved from the patients files, and histologic features were reviewed from hematoxylin and eosin-stained histologic slides.

RESULTS

There were 22 ossifying fibromas (OFs), 21 fibrous dysplasias (FDs) and 100 osseous dysplasias (ODs; 65 florid, 18 focal, and 17 periapical). The mean age of the FD/OF patients was a decade lower than those with OD. The mandible was more affected than the maxilla, except in FDs. All FDs and OFs presented local swelling, whereas this was observed in <40% of the ODs. Radiologic images of the florid/periapical ODs and OFs were predominantly mixed, whereas FDs and focal ODs were predominantly radiopaque.

CONCLUSIONS

Florid OD, OF, and FD were the most common diagnoses, and the clinicopathologic and radiologic features were somewhat distinct from the characteristics of other populations.

摘要

目的

本研究旨在报告 143 例良性纤维骨性病变(BFOLs)的临床病理和影像学特征。

研究设计

从患者的病历中检索临床和影像学信息,并从苏木精和伊红染色的组织学切片中回顾组织学特征。

结果

有 22 例骨化纤维瘤(OFs)、21 例纤维结构不良(FDs)和 100 例骨发育异常(ODs;65 例活跃,18 例局灶性,17 例根尖周)。FD/OF 患者的平均年龄比 ODs 患者低十年。下颌骨比上颌骨更容易受到影响,除了 FDs。所有 FDs 和 OFs 均表现为局部肿胀,而 ODs 中仅有<40%表现出这种情况。活跃/根尖周 ODs 和 OFs 的影像学图像主要为混合性,而 FDs 和局灶性 ODs 主要为阻射性。

结论

活跃性 OD、OF 和 FD 是最常见的诊断,其临床病理和影像学特征与其他人群的特征有些不同。

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