University of Glasgow Sleep Centre, Sackler Institute of Psychobiological Research and Institute of Neuroscience & Psychology, College of Medical, Veterinary & Life Sciences, University of Glasgow, G51 4TF, Scotland.
J Clin Psychiatry. 2012 Dec;73(12):e1478-84. doi: 10.4088/JCP.12m07954.
To profile the daytime impact of the proposed DSM-5 insomnia disorder diagnosis, with and without mental health, physical health, or other sleep disorder comorbidities; to better understand how specific daytime symptom patterns are associated with nighttime sleep in insomnia; and to compare childhood-onset and adulthood-onset insomnia disorder with respect to daytime dysfunction.
Data were derived from the Great British Sleep Survey (GBSS), an open-access online population survey completed by adults who had a valid postcode and were residents of the United Kingdom. The primary variables of interest were the 6 areas that, according to the proposed DSM-5 criteria, may be impacted in the daytime by insomnia disorder: energy, concentration, relationships, ability to stay awake, mood, and ability to get through work. These variables were compared for those with versus those without insomnia disorder and across 5 insomnia subtypes (difficulty initiating sleep, difficulty maintaining sleep, early morning awakening, a combination of these 3 core symptoms, or nonrestorative sleep). Clinically comorbid insomnia presentations (insomnia disorder with poor mental health/poor physical health/additional sleep disorder symptoms) and insomnia disorder of childhood versus adult onset were also evaluated.
A total of 11,129 participants (72% female; mean age = 39 years) completed the GBSS between March 2010 and April 2011, of whom 5,083 screened as having possible insomnia disorder. Compared with those who did not have insomnia disorder, those with insomnia disorder reported greater impairment in all areas of daytime functioning (Cohen d range, 0.68-1.30). The greatest effects reflected negative impact on energy and mood. Participants with a combination of insomnia symptoms tended to be the most impaired (Cohen d range, 0.10-0.23), whereas no consistent differences emerged between the other 4 subtypes. Finally, individuals who had both insomnia disorder and poor mental health were consistently the most impaired comorbid group (Cohen d range, 0.15-0.65), and childhood-onset insomnia disorder had greater daytime impact than adult-onset insomnia disorder (P < .05 for energy; P < .01 for mood, concentration, and getting through work).
The severity of daytime impact of DSM-5 insomnia disorder varies by insomnia type. This finding has implications for the evaluation and management of insomnia in clinical practice.
描述 DSM-5 失眠障碍诊断在白天的影响,包括有和没有心理健康、身体健康或其他睡眠障碍共病的情况;更好地了解特定的日间症状模式如何与失眠夜间睡眠相关联;并比较儿童期和成年期失眠障碍在日间功能障碍方面的差异。
数据来自英国大睡眠调查(GBSS),这是一项开放获取的在线人群调查,由有有效邮政编码并居住在英国的成年人完成。主要感兴趣的变量是根据 DSM-5 标准可能在白天受到失眠障碍影响的 6 个领域:精力、注意力、人际关系、保持清醒的能力、情绪和完成工作的能力。将这些变量与有和没有失眠障碍的人进行比较,并比较 5 种失眠亚型(入睡困难、睡眠维持困难、早醒、这 3 个核心症状的组合或非恢复性睡眠)。还评估了临床合并失眠表现(失眠障碍伴心理健康不良/身体健康不良/其他睡眠障碍症状)和儿童期与成年期发病的失眠障碍。
共有 11129 名参与者(72%为女性;平均年龄为 39 岁)在 2010 年 3 月至 2011 年 4 月期间完成了 GBSS,其中 5083 人筛查为可能患有失眠障碍。与没有失眠障碍的人相比,有失眠障碍的人在所有白天功能领域的损害程度更大(Cohen d 范围,0.68-1.30)。最大的影响反映了对精力和情绪的负面影响。同时存在失眠症状的参与者受影响最严重(Cohen d 范围,0.10-0.23),而其他 4 个亚型之间没有出现一致的差异。最后,同时患有失眠障碍和心理健康不良的个体是受影响最严重的共病组(Cohen d 范围,0.15-0.65),并且儿童期发病的失眠障碍比成年期发病的失眠障碍对白天的影响更大(在精力方面,P <.05;在情绪、注意力和完成工作方面,P <.01)。
DSM-5 失眠障碍的白天影响的严重程度因失眠类型而异。这一发现对临床实践中失眠的评估和管理具有意义。