Center for Interdisciplinary Research in Women's Health, University of Texas Medical Branch, United States.
Vaccine. 2013 Feb 6;31(8):1138-40. doi: 10.1016/j.vaccine.2012.12.051. Epub 2013 Jan 2.
Little is known about initiation and completion among males who received the HPV vaccine on an off-label basis before 2009. This study utilized administrative claims data from a private insurance company to examine completion of the 3 dose HPV series among 514 males who initiated the vaccine between 2006 and May of 2009. Frequencies of HPV vaccination were examined and multivariate logistic regression estimated the odds of completing the entire series within 365 days of initiation. We found that only 21% of male initiators completed all 3 vaccine doses within 12 months and completion decreased over time. Series completion did not vary significantly by provider type. These findings suggest that difficulties may be encountered in fully vaccinating enough males to achieve adequate herd immunity in the future.
在 2009 年之前，根据标签外适应证接种 HPV 疫苗的男性中，对于其接种的启动和完成情况知之甚少。本研究利用一家私人保险公司的行政索赔数据，对 514 名于 2006 年至 2009 年 5 月期间启动 HPV 疫苗接种的男性进行了分析，以检查其是否完成了 3 剂 HPV 系列接种。分析了 HPV 疫苗接种的频率，并使用多变量逻辑回归估计了在启动后 365 天内完成整个系列接种的可能性。结果发现，只有 21%的男性启动者在 12 个月内完成了所有 3 剂疫苗接种，且完成率随时间推移而降低。系列接种完成情况与提供者类型无显著差异。这些发现表明，未来可能难以充分为足够数量的男性接种疫苗，以实现足够的群体免疫。
