Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Eur J Pediatr. 2013 Mar;172(3):289-92. doi: 10.1007/s00431-012-1921-3. Epub 2013 Jan 5.
Drug therapy is a very powerful tool to improve the medical outcome of children. Despite this fact, pediatricians still commonly prescribe drug formulations that were developed for adults. In this series of educational papers related to pediatric clinical pharmacology, we aim to raise awareness on different aspects of clinical pharmacology in children, covering neonatal clinical pharmacology, formulation-related issues, ethical aspects of clinical research, pharmacovigilance, and training in pediatric clinical pharmacology. We want to illustrate the relevance of this re-emerging research field for the practicing clinician, although we are very much aware that these topics do not fully cover the multifaceted landscape of pediatric clinical pharmacology. We hope that many readers will reconsider their daily clinical practices and will be stimulated to collaborate to further improve pediatric drug therapy throughout Europe and beyond.
药物治疗是改善儿童医疗效果的非常有力的工具。尽管如此,儿科医生仍然经常开出处方药物,这些药物是为成年人开发的。在这一系列与儿科临床药理学相关的教育论文中,我们旨在提高对儿童临床药理学不同方面的认识,涵盖新生儿临床药理学、制剂相关问题、临床研究的伦理方面、药物警戒和儿科临床药理学培训。我们想说明这个重新出现的研究领域与临床医生的相关性,尽管我们非常清楚这些主题并没有完全涵盖儿科临床药理学的多方面。我们希望许多读者会重新考虑他们的日常临床实践,并受到激励,在整个欧洲乃至更广泛的地区合作,以进一步改善儿科药物治疗。