Abramidze T, Gotua M, Rukhadze M, Gamkrelidze A
Center for Allergy and Immunology Research, Tbilisi, Georgia.
Georgian Med News. 2012 Dec(213):48-51.
All existing contemporary data are indicating a relatively low prevalence of asthma in Georgia. The aim of the study, which was undertaken as part of ISAAC Phase II, was to assess some potential risk factors of asthma among schoolchildren in Georgia. In this study the current wheezing was revealed in 9.2% of 9 to 11-year-old children. The presence of asthma symptoms was strongly associated with presence of symptoms of rhino-conjunctivitis (OR=8.60, 95% CI=4.82-15.33, p=0.000) and eczema (OR=5.30, 95% CI=2.80-10.04, p=0.000). The logistic regression analysis revealed that environmental factor such as dampness/moulds at home, in addition to family history of allergy, was significant risk factor for asthma in Georgia. Future epidemiological study of risk factors for asthma, at both the host and environmental level, is desirable in order to help detect strategies of allergen avoidance.
所有现有当代数据均表明，格鲁吉亚哮喘患病率相对较低。作为国际儿童哮喘及过敏研究（ISAAC）第二阶段的一部分开展的这项研究，旨在评估格鲁吉亚学龄儿童中哮喘的一些潜在风险因素。在这项研究中，9至11岁儿童中有9.2%出现当前喘息症状。哮喘症状的出现与鼻结膜炎症状（比值比=8.60，95%置信区间=4.82 - 15.33，p = 0.000）和湿疹（比值比=5.30，95%置信区间=2.80 - 10.04，p = 0.000）的存在密切相关。逻辑回归分析显示，除了过敏家族史外，家中潮湿/霉菌等环境因素是格鲁吉亚哮喘的重要风险因素。为了帮助探寻避免接触过敏原的策略，今后有必要在宿主和环境层面开展哮喘风险因素的流行病学研究。
