Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM U964, Université de Strasbourg, F-67404 Illkirch, Cité Universitaire de Strasbourg, France.
Development. 2013 Feb 1;140(3):487-91. doi: 10.1242/dev.087577.
To ensure species continuity, the tantalising developmental plasticity of early embryonic cells, also called totipotency, must be transmitted to the offspring. This responsibility rests within the reproductive cell lineage: the germ line. At the recent EMBO/EMBL symposium 'Germline - Immortality through Totipotency', researchers discussed the mechanisms that establish and control totipotency, with an eye towards the mechanisms that may endow germ cells with the ability to propagate totipotency across generations.
为了确保物种的连续性,早期胚胎细胞令人着迷的发育可塑性,也称为全能性,必须传递给后代。这个责任在于生殖细胞系:生殖细胞系。在最近的 EMBO/EMBL 研讨会“生殖细胞-通过全能性实现不朽”上,研究人员讨论了建立和控制全能性的机制,着眼于赋予生殖细胞传播全能性的能力的机制跨越几代人。