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In vitro cytotoxicity of silver nanoparticles on human periodontal fibroblasts.银纳米颗粒对人牙周膜成纤维细胞的体外细胞毒性
J Clin Pediatr Dent. 2011 Fall;36(1):37-41. doi: 10.17796/jcpd.36.1.d677647166398886.
2
Bactericidal capacity of silver nanoparticles associated with Gantrez S-97 on Streptococcus mutans.与甘膦树脂S-97相关的银纳米颗粒对变形链球菌的杀菌能力。
J Clin Pediatr Dent. 2010 Winter;35(2):183-5. doi: 10.17796/jcpd.35.2.c61l421mj0655lgm.
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The bactericidal effect of silver nanoparticles.银纳米颗粒的杀菌作用。
Nanotechnology. 2005 Oct;16(10):2346-53. doi: 10.1088/0957-4484/16/10/059. Epub 2005 Aug 26.
4
The estimation of the bactericidal power of the blood.血液杀菌能力的评估。
J Hyg (Lond). 1938 Nov;38(6):732-49. doi: 10.1017/s002217240001158x.
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Fabrication, characterization of chitosan/nanosilver film and its potential antibacterial application.壳聚糖/纳米银膜的制备、表征及其潜在的抗菌应用。
J Biomater Sci Polym Ed. 2009;20(14):2129-44. doi: 10.1163/156856209X410102.
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Efficacy of silver diamine fluoride for Arresting Caries Treatment.氟化氨银用于龋齿治疗的疗效。
J Dent Res. 2009 Jul;88(7):644-7. doi: 10.1177/0022034509338671.
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Silver nanoparticles in therapeutics: development of an antimicrobial gel formulation for topical use.治疗中的银纳米颗粒：用于局部应用的抗菌凝胶制剂的研发
Mol Pharm. 2009 Sep-Oct;6(5):1388-401. doi: 10.1021/mp900056g.
8
Silver nanoparticles as a new generation of antimicrobials.银纳米颗粒作为新一代抗菌剂。
Biotechnol Adv. 2009 Jan-Feb;27(1):76-83. doi: 10.1016/j.biotechadv.2008.09.002. Epub 2008 Sep 30.
9
Experimental antimicrobial orthodontic adhesives using nanofillers and silver nanoparticles.使用纳米填料和银纳米颗粒的实验性抗菌正畸粘合剂。
Dent Mater. 2009 Feb;25(2):206-13. doi: 10.1016/j.dental.2008.06.002. Epub 2008 Jul 15.
10
The use of nanoparticles in anti-microbial materials and their characterization.纳米颗粒在抗菌材料中的应用及其表征。
Analyst. 2008 Jul;133(7):835-45. doi: 10.1039/b715532h. Epub 2008 Mar 12.

纳米银基无机抗菌剂（诺瓦龙（®））对变形链球菌的最低抑菌浓度和最低杀菌浓度的评估。

Evaluation of minimum inhibitory and minimum bactericidal concentration of nano-silver base inorganic anti-microbial agent (Novaron(®)) against streptococcus mutans.

作者信息

Holla Goda, Yeluri Ramakrishna, Munshi Autar Krishen

机构信息

Department of Pedodontics and Preventive Dentistry, Kanti Devi Denta College and Hospital, Mathura, Uttar Pradesh, India.

出版信息

Contemp Clin Dent. 2012 Jul;3(3):288-93. doi: 10.4103/0976-237X.103620.

DOI:10.4103/0976-237X.103620
PMID:23293483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3532790/
Abstract

OBJECTIVE

We attempted to find the possibility of determining the minimum inhibitory concentration and minimum bactericidal concentration needed for nano-silver base inorganic anti-microbial agent (Novaron(®) AG 300, AG 1100) against Streptococcus mutans in vitro using broth dilution assay.

MATERIALS AND METHODS

An ampoule of freeze-dried S. mutans NCTC reference strain was revived, and the colony-forming units (CFU) were calculated. The MIC and MBC was determined by broth dilution assay using different concentrations of Novaron(®) AG 300 and Novaron(®) AG 1100 against 1 × 10(5) CFU/ml of S. mutans.

RESULTS

The MIC and MBC of Novaron(®) AG 300 and Novaron(®) AG 1100 against S. mutans were found to be 40 μg/ml.

CONCLUSIONS

Novaron(®) has anti-bacterial effect against S. mutans. Further studies are needed to explore the applicability of these silver-supported anti- microbial agents in clinical dentistry.

摘要

目的

我们试图通过肉汤稀释法，找出测定纳米银基无机抗菌剂（诺瓦龙（®）AG 300、AG 1100）对变形链球菌的体外最低抑菌浓度和最低杀菌浓度的可能性。

材料与方法

复苏一支冻干的变形链球菌NCTC参考菌株安瓿，计算菌落形成单位（CFU）。采用肉汤稀释法，使用不同浓度的诺瓦龙（®）AG 300和诺瓦龙（®）AG 1100，针对1×10⁵CFU/ml的变形链球菌测定最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。

结果

发现诺瓦龙（®）AG 300和诺瓦龙（®）AG 1100对变形链球菌的最低抑菌浓度和最低杀菌浓度均为40μg/ml。

结论

诺瓦龙（®）对变形链球菌有抗菌作用。需要进一步研究以探索这些载银抗菌剂在临床牙科中的适用性。