Department of Radiology, Medical School, Dicle University, Yenişehir, 21280, Diyarbakır, Turkey.
Breast J. 2013 Mar-Apr;19(2):156-61. doi: 10.1111/tbj.12069. Epub 2013 Jan 7.
To determine if the specimen without calcification, as depicted on specimen radiography, made any contribution to the final histopathological diagnosis in comparison to the specimen with calcification. The records of 1312 stereotactic vacuum-assisted biopsies for breast microcalcifications between February 2000 and December 2010 were reviewed retrospectively. Following specimen x-ray the biopsy tissues with and without microcalcifications were sent in two separate pots (pot 1 and pot 2 respectively). The number of cores in each pot and the number of calcium specks within the cores were recorded. In 1135 of the 1312 (86%) cases the histopathological findings were similar for pot 1 and pot 2. In 165 cases (13%) the diagnosis was made solely on pot 1 while cores in pot 2 did not reveal any additional pathology. In 12 biopsies (1%) the significant pathology was only present in the specimen without any calcification. For "microcalcification only" breast lesions the specimen containing calcium will yield a correct diagnosis in 99% of cases. Cores containing no calcification rarely contribute to the diagnosis on their own, but in 87% of cases an accurate diagnosis would still have been made even if the targeted calcification had been missed.
为了确定与有钙化的标本相比，影像学检查未见钙化的标本对最终的组织病理学诊断有无贡献。回顾性分析了 2000 年 2 月至 2010 年 12 月期间 1312 例立体定向真空辅助乳腺微钙化活检的记录。在进行标本 X 线检查后，将有和无微钙化的活检组织分别放入两个单独的小瓶（分别为小瓶 1 和小瓶 2）中。记录每个小瓶中的核心数量和核心内钙斑的数量。在 1312 例中的 1135 例（86%）中，小瓶 1 和小瓶 2 的组织病理学发现相似。在 165 例（13%）中，仅通过小瓶 1 做出了诊断，而小瓶 2 中的核心未显示任何其他病理学改变。在 12 例活检（1%）中，无钙化的标本中仅存在重要的病理学改变。对于“仅微钙化”的乳腺病变，含有钙的标本在 99%的情况下可以做出正确的诊断。不含钙化的核心很少单独有助于诊断，但在 87%的情况下，即使未发现目标钙化，仍可以做出准确的诊断。
