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二尖瓣修复:孤立性后叶病变与前叶或双叶病变的比较。

Mitral valve repair: isolated posterior compared to anterior or bileaflet pathology.

作者信息

Spiegelstein Dan, Sternik Leonid, Orlov Boris, Shinfeld Amihai, Feinberg Micha S, Malachy Ateret, Raanani Ehud

机构信息

Department of Cardiac Surgery, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel, Affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

J Card Surg. 2013 Mar;28(2):89-96. doi: 10.1111/jocs.12051. Epub 2013 Jan 7.

Abstract

OBJECTIVES

The results of mitral valve (MV) repair for anterior leaflet pathology (ALP) are considered less favorable than those for posterior leaflet pathology (PLP). We compared clinical and echocardiography outcomes of PLP repair with ALP and/or bileaflet pathology (BLP) repair.

METHODS

Between 2004 and 2011, 407 patients underwent MV repair due to degenerative MV: 276 patients (68%) had PLP and 131 (32%) had ALP/BLP. Mean age was 59 ± 12 and 56 ± 15 years in PLP and ALP/BLP groups, respectively (p = 0.03). Patient characteristics and co-morbidities were similar between groups. Valve repair techniques included leaflet resection (61% and 24%), annuloplasty (99% and 97%), and artificial chordea (46% and 67%), in the PLP and ALP/BLP groups, respectively.

RESULTS

There was one (0.4%) in-hospital death in the PLP group, and none in the ALP/BLP group. Early complication rate was similar between groups. Completed clinical and late echocardiography follow-up was 95% (29 ± 22 months, 1 to 87). Freedom from reoperation was 98% (270/276) and 98% (129/131), and there were three (1%) and three (2%) late deaths, in the PLP and ALP/BLP groups, respectively (NS). Late echocardiography revealed that 89% and 94% of patients (PLP and ALP/BLP groups, respectively) were free from moderate or severe mitral regurgitation (MR) (p = 0.13). All other late valve-related complications were similar between groups.

CONCLUSIONS

Anterior and bileaflet MV disease can be repaired with early and mid-term results similar to those of posterior MV disease. All patients with severe MR due to anterior or posterior pathology should be considered equally for early valve repair.

摘要

目的

二尖瓣(MV)前叶病变(ALP)修复的结果被认为不如后叶病变(PLP)修复的结果。我们比较了PLP修复与ALP和/或双叶病变(BLP)修复的临床和超声心动图结果。

方法

2004年至2011年期间,407例患者因退行性二尖瓣病变接受了MV修复:276例患者(68%)有PLP,131例(32%)有ALP/BLP。PLP组和ALP/BLP组的平均年龄分别为59±12岁和56±15岁(p = 0.03)。两组患者的特征和合并症相似。瓣膜修复技术在PLP组和ALP/BLP组中分别包括瓣叶切除(61%和24%)、瓣环成形术(99%和97%)以及人工腱索(46%和67%)。

结果

PLP组有1例(0.4%)住院死亡,ALP/BLP组无死亡。两组的早期并发症发生率相似。完成临床和晚期超声心动图随访的比例为95%(29±22个月,1至87个月)。PLP组和ALP/BLP组再次手术的自由度分别为98%(270/276)和98%(129/131),分别有3例(1%)和3例(2%)晚期死亡(无显著性差异)。晚期超声心动图显示,PLP组和ALP/BLP组分别有89%和94%的患者无中度或重度二尖瓣反流(MR)(p = 0.13)。两组之间所有其他晚期瓣膜相关并发症相似。

结论

二尖瓣前叶和双叶病变可以修复,早期和中期结果与二尖瓣后叶病变相似。所有因前叶或后叶病变导致严重MR的患者,在早期瓣膜修复方面应被平等对待。

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