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二尖瓣双叶脱垂的修复治疗结果。

Outcomes of mitral valve repair for bileaflet prolapse.

机构信息

Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.

出版信息

J Thorac Cardiovasc Surg. 2012 Apr;143(4 Suppl):S21-3. doi: 10.1016/j.jtcvs.2011.11.014. Epub 2011 Dec 9.

Abstract

OBJECTIVE

Repair of bileaflet prolapse has been considered to be technically demanding and challenging. To assess the reliability and durability of mitral valve repair for bileaflet prolapse, the present study compared the outcomes of mitral valve repair for bileaflet prolapse with those for posterior prolapse.

METHODS

From January 1991 to April 2010, 191 consecutive patients with bileaflet prolapse (group B) underwent mitral valve repair using a combination procedure of expanded polytetrafluoroethylene chordal reconstruction for anterior prolapse, resection suture technique with/without sliding technique for posterior prolapse, and ring annuloplasty. During the same period, 323 patients with posterior prolapse (group P) underwent standard mitral valve repair. Serial echocardiograms were obtained at discharge and 1, 3, 5, and 10 years postoperatively.

RESULTS

The mean age in group B (54 ± 15 years) was significantly younger than that in group P (61 ± 12 years). Survival, including hospital death at 10 years, was superior in group B (group B, 90% ± 3%; group P, 83% ± 3%; P = .046). At 10 years, no significant differences were found between the groups in terms of freedom from recurrent mitral regurgitation of more than mild (group B, 89% ± 3%; group P, 90% ± 2%), freedom from reoperation (group B, 97% ± 2%; group P, 97% ± 1%), and event-free survival (group B, 79% ± 5%; group P, 83% ± 3%).

CONCLUSIONS

The reproducibility and reliability of mitral valve repair for bileaflet prolapse compares favorably with that of posterior leaflet prolapse. Early surgery might be recommended for patients with severe mitral regurgitation owing to bileaflet prolapse.

摘要

目的

二尖瓣双叶脱垂的修复被认为具有较高的技术要求和挑战性。为了评估二尖瓣双叶脱垂修复的可靠性和耐久性,本研究比较了二尖瓣双叶脱垂和后叶脱垂修复的结果。

方法

1991 年 1 月至 2010 年 4 月,191 例二尖瓣双叶脱垂患者(B 组)采用前叶扩张聚四氟乙烯腱索重建术、后叶切除术缝合技术联合/不联合滑动技术、环形瓣环成形术联合进行二尖瓣修复。同期 323 例后叶脱垂患者(P 组)采用标准二尖瓣修复术。术后出院时及 1、3、5、10 年进行连续超声心动图检查。

结果

B 组(54±15 岁)的平均年龄明显低于 P 组(61±12 岁)。B 组的生存率,包括 10 年的院内死亡,优于 P 组(B 组,90%±3%;P 组,83%±3%;P=0.046)。10 年时,两组在中度以上复发性二尖瓣反流(B 组,89%±3%;P 组,90%±2%)、无再手术(B 组,97%±2%;P 组,97%±1%)和无事件生存(B 组,79%±5%;P 组,83%±3%)方面无显著差异。

结论

二尖瓣双叶脱垂修复的可重复性和可靠性与后叶脱垂修复相当。对于二尖瓣双叶脱垂引起的严重二尖瓣反流患者,早期手术可能是推荐的。

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