Vitos Philippshospital, Philippsanlage 101, Riedstadt 64560, Germany.
BMC Psychiatry. 2013 Jan 7;13:10. doi: 10.1186/1471-244X-13-10.
Antonovsky's sense of coherence (SOC) as well as psychoeducational interventions has a convincing impact on the quality of life (QOL) of patients suffering from schizophrenia. This study explores the influence of SOC on QOL among participants of a PEFI group (PG) compared to a control group (CG).
In a quasi-experimental field study 46 schizophrenic outpatients had an option to participate together with their family members the PG (n = 25) or the CG (n = 21). They were assessed amongst others with the Quality of Life Questionnaire (WHOQOL-BREF), the Global Assessment of Functioning Scale (GAF), the Positive and Negative Syndrome Scale (PANSS) and the Sense of Coherence Scale (SOC-29). The efficacy of the PG on QOL was compared to the CG within two different SOC levels.
Before intervention patients with high SOC scores had significant higher levels in GAF and QOL and a trend of lower PANSS scores. The strongest relationship was found between SOC and QOL. Regarding the SOC level after intervention PG participants had higher QOL values than the CG within the last three measurements. The highest benefit due to QOL was observed within PG participants with high SOC scores.
The results of the study suggest that SOC is a good predictive variable for clinical outcomes including QOL. Generally, the influence of the SOC level on QOL was stronger than the effect of PEFI. Hence schizophrenic patients with high SOC scores did benefit most from participating in a PG regarding their QOL. To optimize the effect of PEFI more efforts are needed to enhance the SOC of the participants. Altogether PEFI seems to be an important completion to the standard treatment for schizophrenic outpatients.
Antonovsky 的社会感（SOC）以及心理教育干预对精神分裂症患者的生活质量（QOL）具有令人信服的影响。本研究探讨了 SOC 对接受心理教育和家庭干预（PEFI）组（PG）参与者与对照组（CG）参与者的 QOL 的影响。
在一项准实验性现场研究中，46 名精神分裂症门诊患者可以选择与他们的家庭成员一起参加 PG（n = 25）或 CG（n = 21）。他们除其他外还接受了生活质量问卷（WHOQOL-BREF）、功能总体评估量表（GAF）、阳性和阴性综合征量表（PANSS）和社会感量表（SOC-29）的评估。PG 对 QOL 的疗效与 CG 在 SOC 两个不同水平进行了比较。
在干预前，SOC 评分较高的患者在 GAF 和 QOL 方面的得分明显较高，PANSS 评分也呈下降趋势。SOC 与 QOL 之间的关系最强。干预后，PG 参与者的 SOC 水平在最后三次测量中均高于 CG，PG 参与者的 QOL 值高于 CG。PG 参与者的 SOC 评分较高，其 QOL 获益最大。
研究结果表明，SOC 是包括 QOL 在内的临床结局的良好预测变量。一般来说，SOC 水平对 QOL 的影响强于 PEFI 的影响。因此，SOC 评分较高的精神分裂症患者从参加 PG 中获益最大，特别是在 QOL 方面。为了优化 PEFI 的效果，需要更多的努力来增强参与者的 SOC。总的来说，PEFI 似乎是精神分裂症门诊患者标准治疗的重要补充。
