Griesdale Donald E G, Sekhon Mypinder S, Henderson William R
Crit Care. 2013 Jan 7;17(1):401. doi: 10.1186/cc11888.
The observational literature suggests that hypernatremia is associated with worse outcomes in patients with traumatic brain injury. In a previous issue of Critical Care, Wells and colleagues add to this literature by failing to show an association between hypernatremia and reduced intracranial pressure. However, we must bear in mind many limitations of observational methods before eliminating hyperosmolar therapy from our armamentarium.
观察性文献表明，高钠血症与创伤性脑损伤患者的不良预后相关。在《重症监护》的上一期中，韦尔斯及其同事补充了这方面的文献，他们未能证明高钠血症与颅内压降低之间存在关联。然而，在将高渗疗法从我们的治疗手段中剔除之前，我们必须牢记观察性方法存在的诸多局限性。
