MRC/Wits Rural Public Health, Health Transitions Research Unit (Agincourt), Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Health and Population Division of Public Health, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Int J Stroke. 2013 Oct;8 Suppl A100:76-80. doi: 10.1111/j.1747-4949.2012.00955.x. Epub 2013 Jan 7.
South Africa is experiencing epidemiological transition, with the burden of chronic diseases increasing. Stroke is currently the second leading cause of death in South Africa; however, limited data are available on incidence, prevalence and resulting disability. Quantifying the epidemiological parameters and disease burden is important in the planning of health services.
To synthesize the data surrounding stroke in South Africa and calculate disability adjusted life years attributable to stroke in South Africa in 2008.
We undertook a systematic review to identify studies on the prevalence and mortality of stroke in South Africa. We used the DisMod program to calculate missing epidemiological parameters, in particular incidence and duration. Using these values, we calculated the burden of disease in years of life lost (YLL), years lived with disability (YLD) and disability adjusted life years (DALY).
Data on prevalence and mortality of stroke in South Africa are scarce. We estimate there are 75,000 strokes in South Africa each year, with 25,000 of these fatal within the first month. The burden of disease due to stroke in South Africa was 564,000 DALYs. Of this, 17% is contributed by YLD (14-20% in sensitivity analysis).
This study provides information on prevalence, incidence and disease burden of stroke at the national level in South Africa. The results of this analysis will enable further work on priority setting and health service planning for primary and secondary prevention of stroke in South Africa.
南非正经历着流行病学转变，慢性病负担不断增加。中风目前是南非的第二大致死原因；然而，关于发病率、患病率和由此导致的残疾的有限数据。量化流行病学参数和疾病负担对于卫生服务规划非常重要。
综合南非中风的数据，并计算 2008 年南非中风归因于残疾调整生命年。
我们进行了一项系统综述，以确定南非中风患病率和死亡率的研究。我们使用 DisMod 程序计算缺失的流行病学参数，特别是发病率和持续时间。利用这些值，我们计算了疾病负担的年生命损失（YLL）、残疾生存年（YLD）和残疾调整生命年（DALY）。
南非中风的患病率和死亡率数据稀缺。我们估计南非每年有 75,000 例中风，其中 25,000 例在第一个月内死亡。南非中风的疾病负担为 564,000 DALY。其中，17%由 YLD 造成（在敏感性分析中为 14-20%）。
本研究提供了南非全国范围内中风的患病率、发病率和疾病负担信息。该分析的结果将有助于进一步开展南非中风一级和二级预防的优先事项设定和卫生服务规划工作。
