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青少年电抽搐治疗:来自印度北部的回顾性研究。

Electroconvulsive therapy in adolescents: a retrospective study from north India.

机构信息

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J ECT. 2013 Jun;29(2):122-6. doi: 10.1097/YCT.0b013e31827e0d22.

Abstract

OBJECTIVES

There are minimal data on the use of electroconvulsive therapy (ECT) in adolescents from India. The present study aimed to evaluate the clinical profile and effectiveness of ECT in adolescents (aged 13-18 years).

METHODS

A retrospective chart review was carried out to identify adolescents (aged 13-18 years) who had received ECT during the period 1999-2011. During the study period, 39 such patients received ECT; complete records of 25 patients were available. Details regarding their sociodemographic, clinical, and treatment data were extracted from these records for the present study.

RESULTS

During the study period, 658 patients received ECT, of which 39 were aged 18 or younger (5.9%). Schizophrenia (n = 14; 56%) was the commonest diagnosis for which ECT was used in adolescents, followed by depression (n = 3; 12%). Catatonic symptoms (n = 17; 68%) were the most common symptoms among these subjects. Electroconvulsive therapy was considered as a treatment of choice taking the clinical picture account in about three fourths of the patients (n = 19; 76%). The mean (SD) numbers of ECTs administered per patient were 10.1 (4.87) (range, 2-21). The mean (SD) response rate to ECT was 76% (23.3%) (range, 31%-100%). Response rates according to diagnosis were the following: 76.3% for schizophrenia, 87.2% for depression, 81.8% for psychosis (not otherwise specified), and 77.7% for acute and transient psychosis. Response rate in patients with catatonia was 91.6%. Prolonged seizures, nausea and vomiting, and headache were reported in 2 cases each.

CONCLUSION

Electroconvulsive therapy is used less frequently in children and adolescents compared to the older patients. This study shows that ECT is effective in the treatment of severe psychiatric disorders in adolescents and is associated with the same frequency of adverse effects as the adults.

摘要

目的

印度关于电抽搐治疗(ECT)在青少年中应用的数据很少。本研究旨在评估 ECT 在青少年(13-18 岁)中的临床特征和疗效。

方法

对 1999 年至 2011 年间接受 ECT 的青少年(13-18 岁)进行回顾性病历分析。在研究期间,有 39 例患者接受了 ECT;其中 25 例患者的完整记录可供分析。从这些记录中提取他们的社会人口学、临床和治疗数据的详细信息,用于本研究。

结果

在研究期间,有 658 例患者接受了 ECT,其中 39 例年龄在 18 岁以下(5.9%)。ECT 最常用于治疗青少年的精神分裂症(n=14;56%),其次是抑郁症(n=3;12%)。这些患者中最常见的症状是紧张症(n=17;68%)。根据临床情况,大约四分之三的患者(n=19;76%)将 ECT 视为首选治疗方法。每位患者平均(SD)接受的 ECT 次数为 10.1(4.87)(范围,2-21)。ECT 的平均(SD)反应率为 76%(23.3%)(范围,31%-100%)。根据诊断的反应率如下:精神分裂症 76.3%,抑郁症 87.2%,未特指的精神病 81.8%,急性和短暂性精神病 77.7%。紧张症患者的反应率为 91.6%。有 2 例患者出现癫痫持续状态、恶心和呕吐、头痛。

结论

与老年患者相比,ECT 在儿童和青少年中应用较少。本研究表明,ECT 对青少年严重精神障碍的治疗有效,且与成人的不良反应发生率相同。

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